Taking NMN by subcutaneous injection or oral administration can improve the immune cells in mice that attack cancer and virus-infected cells.
As the average life expectancy of human beings increases, people’s poor health and age-related diseases last longer, resulting in significant economic and social costs. An important factor leading to age-related diseases and their progression is decreased immune function. Specifically, NK cells, which terminate cancer and virus-infected cells, become less effective. Currently, there is no remedy that can restore the function of NK cells during the aging process. Therefore, compounds that stimulate the activation of NK cells can prevent or slow down the progression of age-related diseases.
Many aspects of immunity will decline with age, and the function of NK immune cells is no exception.
As we age, the age-related deterioration of immune function is related to the level of a basic molecule called nicotinamide adenine dinucleotide (NAD+), which also declines with age. However, increasing the level of NAD+ has been shown to improve the immune function of mice.